New high-resolution speleothem records from China and India, together with isotope-enabled climate models, show that abrupt glacial ocean circulation recoveries took centuries, not decades—a finding with important implications for how we assess future Atlantic circulation change. The work is published in the journal Science.
Over the past 100,000 years, hooved mammals that migrate have experienced a higher rate of extinction compared to nonmigratory species, according to a study being published Nov. 5 in the journal PLOS Biology by Joel Abraham at Princeton University, U.S., and colleagues.
Cannabis is one of the most commonly used psychoactive plants today. However, it is difficult to determine archaeologically how cannabis was used in prehistoric times. Plant parts such as flowers, leaves and resins are perishable and therefore rarely survive. It is known that cannabis served various purposes, such as the production of oil or fiber, and was not used solely as medicine or a drug.
Researchers at the Wyss Institute at Harvard University, Boston Children's Hospital, and Harvard Medical School (HMS) have developed FIND, a drug discovery platform that searches large libraries for molecules that modulate binding interactions between two proteins. FIND uses DNA nanoswitches to select drug candidates based on their effects on these protein-protein interactions, rather than simply whether they bind to a single target protein, giving it a key advantage over conventional binding-based screening.
A previously unrecognized weakness in the immune defenses against certain blood neoplasms could offer a promising target for future treatments. Researchers have discovered that natural killer cells, which normally help the body eliminate malignant cells, remain remarkably active in patients with a particular genetic form of blood neoplasms. However, their ability to fight the disease appears to be restricted by an inhibitory molecular signal.
Scientists have developed a remarkable new membrane that separates crude oil at room temperature, using the oil itself to create microscopic filtration channels. The breakthrough could cut refining energy consumption by nearly 32%, carbon emissions by almost 38%, and operating costs by 36%, potentially transforming one of the world's most energy-intensive industries.
Scientists have discovered how to reprogram the internal structure of glass using a special molecule that rearranges chemical bonds while lowering the melting temperature. The breakthrough could unlock entirely new glass materials with precisely controlled magnetic and optical properties, opening possibilities for advanced electronics, sensors, and other technologies.
A groundbreaking discovery is rewriting the story of human evolution, revealing that an ancient human species once thought to be an evolutionary dead end may have left genetic traces in people alive today. By extracting proteins from 400,000-year-old Homo erectus teeth discovered in China, scientists uncovered evidence suggesting that these early humans interbred with Denisovans, another mysterious ancient human group. That genetic connection may have eventually reached modern populations in the Philippines, Papua New Guinea, and other parts of Southeast Asia.
Scientists have uncovered a surprising link between Alzheimer’s-related protein buildup, disrupted brain waves during deep sleep, and fading memory. The findings suggest that hidden changes in how the brain processes memories overnight may contribute to age-related memory loss long before Alzheimer’s symptoms appear.
Scientists have developed a revolutionary gel that could regrow lost tooth enamel by harnessing minerals naturally found in saliva, potentially overcoming one of dentistry’s biggest limitations. The regenerated enamel behaves much like healthy enamel, raising hopes for a simple treatment that could repair damaged teeth, prevent decay, and reduce sensitivity.
